| Home | E-Submission | Sitemap | Contact Us
top_img
JPTM > Volume 44(2); 2010 > Article
The Korean Journal of Pathology 2010;44(2): 220-224.
doi: https://doi.org/10.4132/KoreanJPathol.2010.44.2.220
Fine Needle Aspiration Biopsy of a Myxoid Leiomyosarcoma with Epithelioid Features and It Metastasized to the Abdominal Wall: A Case Report.
Lee So Maeng, Hiun Suk Chae, Anhi Lee, Yongan Chung, Kyo Young Lee
1Department of Hospital Pathology, Incheon St. Mary's Hospital, The Catholic University of Korea College of Medicine, Incheon, Korea. mls1004@catholic.ac.kr
2Department of Internal Medicine, Incheon St. Mary's Hospital, The Catholic University of Korea College of Medicine, Incheon, Korea.
3Department of Radiology, Incheon St. Mary's Hospital, The Catholic University of Korea College of Medicine, Incheon, Korea.
ABSTRACT
We present the cytologic findings observed in a fine needle aspiration biopsy specimen of a rare myxoid variant of leiomyosarcoma with epithelioid features and the tumor had metastasized to the abdominal wall. The aspirate showed hypercellularity in a hemorrhagic background. Some large 3-dimensional aggregates of spindle cells were observed. Each cell had a solitary ovoid-to-elongated nucleus with finely granulated chromatin, one or two small distinct nucleoli and an irregular nuclear membrane. There were irregular fascicles of spindle cells with cigar-shaped, blunt-ended nuclei admixed with inflammatory cells. Epithelioid cells with a rather narrow, dense cytoplasmic rim and a well-defined cell border were embedded in a myxoid matrix in a cord-like and cluster arrangement. The matrix appeared as a pale green substance with sharply defined edges. There were very few mitoses. These cytologic features were the same as those of a uterine myxoid leiomyosarcoma that was surgically excised 7 years ago, and immunohistochemical staining revealed the smooth muscle origin of the tumor.
Key Words: Cytology; Biopsy, fine-needle; Uterus; Leiomyosarcoma; Neoplasm metastasis